HML2 |
HMMR |
HMGN2(17-48) |
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[high molecular mass inhibitor factor] This biochemically uncharacterized factor of 115 kDa is found in the conditioned medium of a CD1(+) and CD8(+) T-cell clone (GI-CO-T-9) established from a culture of an acute T-lymphoblastic leukemia (T-ALL).
This clone does not produce TNF-alpha, TNF-beta, IFN-alpha, IFN-tau, IL1, IL2 and has no natural killer-like activity. HMMIF inhibits the responsiveness of normal peripheral blood mononuclear cells to phytohemagglutinin.
A factor of 80 kDa, designated LMMIF (
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