HbA(137-141) |
Hb-associated macrophages |
rabbit vaginal fluid hemoglobin-alpha peptide |
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[hemoglobin anti-HIV peptide-25] This synthetic peptide is based on the sequence of a fragment of human hemoglobin-alpha, HbA(88-112), AHKLRVDPVNFKLLSHCLLVTLAAH (for the equivalent rabbit hemoglobin-alpha sequence see also: RVFHbalphaP [rabbit vaginal fluid hemoglobin-alpha peptide]). HbAHP-25 (AHKLRVDPVNCKLLSHCLLVTLARH) binds to CD4 binding region of gp120 of HIV1, is specific for HIV1. The peptide interferes with gp120 - CD4 interaction. It is active against HIV1 strains utilising CCR5 or CXCR4
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