HbB(35-41) |
HbB(111-146) |
subtractive immunization M(+)HEp3 associated 135 kDa protein |
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[hemoglobin-beta(99-110)] variously termed Hp-beta(99-110) or VD-Hp-beta. This bioactive fragment of Hemoglobin-beta with the sequence VDPENFRLLCNM (Val-Asp-Pro-Glu-Asn-Phe-Arg-Leu-Leu-Cys-Asn-Met) shows sequence similarity with other hemoglobin fragments (see: Hemopressin). It appears to be an endogenous peptide in mouse brain and shows activity as a peptide endocannabinoid that activates CB1 and CB2 cannabinoid receptors (Gomes et al, 2009, 2010).
See also cryptides
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