HCC1[9-74] |
HCD57 |
UMC antigen |
||
[Hydrophis cyanocinctus cathelicidin] This peptide, KFFKRLLKSVRRAVKKFRKKPRLIGLSTLL, from the sea snake Hydrophis cyanocinctus possesses potent broad-spectrum and rapid antimicrobial activity. It is highly stable and shows low cytotoxicity towards mammalian cells. Hc-CATH kills cells by disruption of cell membrane and lysis of bacterial cells. In addition, Hc-CATH shows potent anti-inflammatory activity by inhibiting production of nitric oxide and pro-inflammatory cytokines such as TNF-alpha, IL1-beta, and IL6 induced by bacterial lipopolysaccharide. Hc-CATH directly binds to lipopolysaccharide
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |