Human menopausal gonadotropin |
Human metapneumovirus small hydrophobic protein |
wingless-type MMTV integration site family member 5b |
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[Human metapneumovirus small hydrophobic protein] [HMPV SH protein; HMPV small hydrophobic protein] This small protein of unknown function is encoded by human metapneumovirus, a causative agent of severe respiratory tract disease worldwide. The protein forms oligomeric structures and is thought to act as a channel-forming viroporin that affects membrane permeability (Masante et al, 2014). HMPV SH protein can significantly decrease membrane fusion activity of the virus-encoded F protein, which is necessary and sufficient for both viral binding to the target cell and fusion between the cellular plasma membrane and the viral membrane.
For other relevant entries see also the Pathogenicity/Virulence Factors Dictionary
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