IL1 receptor family

[Interleukin-1 receptor family] The receptors belonging to this family of related proteins contain contain immunoglobulin-like domains in their extracellular portion and most of them are characterized by the presence of an intracellular TIR domain. Some of the family members function as signaling ligand-binding chains. Others function as accessory receptors. Two members are orphan receptors with unknown ligands. Two proteins are unconventional receptors (non-signaling ligand-binding or unable to bind IL1 ligands) (Boraschi and Tagliabue, 2006; O'Neill, 2008)

Members include:

• IL1R1 [Interleukin-1 receptor 1; IL1 receptor R1]

• IL1R2 [ ... ... ... ...
 
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Entry last modified: September 2011