IL1-HY1 |
IL1/IL18 family |
sperm antigen 36 |
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The human IL1-HY2 protein shares significant amino acid sequence similarity (37 %) with the IL1 receptor antagonist, IL1ra, and probably also has a similar three-dimensional structure (Lin et al, 2001; Mulero et al, 1999).
IL1-HY2 protein is secreted from mammalian cells. The recombinant protein binds soluble IL1 receptor type 1. IL1-HY2 is expressed in human skin (basal epithelia), spleen, and tonsil (proliferating B-cells).
The protein is known also as IL1F10 [Interleukin-1 family member 10]. Another designation in databanks is FIL1-theta
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