IL17(+) T-helper cells |
IL18 |
endothelial cell adhesion molecule |
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[IL17-producing Th2 cells; interleukin-17-producing Th2 cells] This cell type has been identified by Wang et al (2010). IL17-Th2 cells constitute a subset of CD4(+) Th2 cells that coexpress the transcription factors GATA-3 (master transcription factor for Th2 development), and the retinoic acid-related orphan receptor ROR-gammat (master transcription factor for Th17 cell development).
IL17-Th2 cells exhibit a memory T-cell phenotype and express CD45RO, CCR7, CD27, and CD62L, as well as CCR4 and
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