IL17RD |
IL17 receptor A |
Heparin binding growth factor-7 |
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[interleukin-17 receptor E; IL17 receptor E] Mouse IL17RE has been identified by Li et al (2006) as a member of the IL17 receptor family. Mouse IL17RE is expressed in limited tissues (lung, kidney, stomach, intestine, testis) and can be detected also in numerous tumor cell lines. A mitogenic effect is observed in BaF3 cells stably transfected with the chimeric receptor fused by the ectodomain of erythropoietin receptor with the transmembrane and endomain of IL17RE in a serum-dependent but erythropoietin independent manner. This involves activation of RAS/MAPK signaling pathway. Chang et al (2011) have reported expression of IL17RE in Th17 cells
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