IpaD |
IPAF inflammasome |
C-type carbohydrate recognition domain |
||
[ICE protease-activating factor] This protein is related to APAF-1 and is identical with CARD12. It has been described independently also as CLAN [CARD LRR and NACHT domain-containing protein]. The approved gene symbol for this protein is NLRC4 [NLR family, CARD domain containing 4].
IPAF contains an aminoterminal CARD domain, a central nucleotide-binding domain, and a carboxyterminal regulatory leucine-rich repeat domain (LRR). The CARD domain of IPAF associates directly and specifically with the CARD domain of the zymogen form of caspase-1
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |