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IPO-24

The antigen identified by a monoclonal antibody of this name was obtained after immunization with human B-cell lines RPMI 1788, DAUDI, and spleen cells from a patient with hairy cell leukemia. IPO-24 antigen defines an antigen expressed specifically on B-cells. The antigen is expressed throughout B-cell ontogeny from pre-B-cells to the B-cell blast stage. MAb IPO-4 detected an antigen of activated T and B lymphocytes. These mAbs are useful tools in the leukemia and lymphoma phenotypic characterization and classification.

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