IR1 |
IRAK |
Cytomegalovirus UL123 protein |
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[Innate response activator B-cells] This cell type develops as a subpopulation of peritoneal B-1a cells (see: B-1 cells). IRA B-cells produce the growth factor GM-CSF (Rauch et al, 2012). IRA-B cells also produce IL3 but not pro-IL1-beta, IL6, and TNF-alpha or IL10. The cells are CD19(+) B220(+) and express MHC II. IRA-B cells are CD23(low) CD43(high) CD93(+) CD21(low) CD138(+) VLA-4(high) LFA-1(high)
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