K4.2 |
K60 |
leucine-rich repeat-containing G-protein-coupled receptor 8 |
||
The gene for K5-5 has been cloned from the human cell line KU-812 (immature basophils). Significant levels of its mRNA are expressed in human basophils and expression is upregulated by IL5. Cells engineered to express the receptor respond to the CC-Chemokines, MIP-1-alpha, RANTES, and MCP-1, but not to MCP-2, MIP-1-beta, or IL8 (Power et al, 1995).
The new designation for this receptor is CCR4.
... ... ... ... ... Subscribe to continue reading! ... ...
Content view restricted ! |