kit |
KITL |
Vaccinia virus A53R protein |
||
A human T-cell line established from a patient with T-cell chronic lymphocytic leukemia. The cells express the markers CD3, CD4 but not CD8. The cells are not infected with HTLV I or II (Hori et al, 1987). Kit225 cells express a large amount of IL2 receptors constitutively, and their growth is absolutely dependent on IL2 (see also: Factor-dependent cell lines). No other stimuli, such as lectins or antigens, are required for maintaining the responsiveness to IL2 (Hori et al, 1987).
Burton et al (1994), in an attempt to characterize the interleukin
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