Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-Phe |
LEVD-AFC |
LMIR6 |
||
The synthetic tetrapeptide LEVD (Leu-Glu-Ala-Asp) conjugated to 7-amino-4-trifluoromethyl coumarin (LEVD-AFC) is a fluorogenic substrate for caspase-4 which is detectable following cleavage of the substituted coumarin moiety from the peptide. This synthetic inhibitor is available coupled to fluoromethylketone (LEVD-fmk) or the N-benzyloxycarbonyl-derivative (zLEVD-fmk).
Leu-Glu-Ala-Asp-aldehyde (LEVD-CHO) is a synthetic caspase-4 inhibitor.
General note on chemical modifications: Practically all of the available caspase inhibitors, be they specific or pan-caspase inhibitors
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R