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Lung-derived growth factor

This factor is found in conditioned medium of lung tissue fragments. It is a mitogen for certain tumor cells that preferentially metastasize into lung tissues (rat mammary adenocarcinoma, murine B6 melanoma). It is not secreted by non-metastasizing cell variants derived from the parent lines. The factor is identical with the iron transport protein Transferrin.

It may be identical with another growth factor called LDGF-1 [lung-derived growth factor-1].

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Entry last modified: January 2002

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