Manduca sexta Periviscerokinin-1 |
mannan-binding lectin |
Gregory antigen |
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(approved gene symbol) [mesencephalic astrocyte-derived neurotrophic factor] This secreted 20 kDa protein was identified originally in a rat cell line established from mesencephalic type 1 astrocytes (Petrova et al, 2003). The human gene has been cloned by Petrova et al (2003). The protein has been identified independently as ARP [arginine-rich protein] and is being referred to also as ARMET [arginine-rich protein mutated in early stage tumors].
Petrova et al (2003) have reported that MANF selectively protects nigral dopaminergic neurons, versus GABAergic or serotonergic neurons. MANF is more selective than GDNF or
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