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MCA-32

[mast cell antigen 32] see approved gene symbol: MILR1 [mast cell immunoglobulin like receptor 1].

Rat and mouse MCA-32 genes encoding this antigen have been described by Pirozzi et al (1995). The MCA-32 gene is highly conserved between rat and mouse, with the two coding regions being 73 % identical. Although MCA-32 appears to be a cell surface antigen, one form seems to be secreted.

MCA-32 mRNA expression is up-regulated upon activation of RBL-2H3 mast cells through the high affinity IgE receptor and is highly abundant in primary peritoneal mast cells. Expression of MCA-32 mRNA is only observed in primary and transformed mast cells from rat ... ... ... ... ... Subscribe to continue reading! ... ...

 

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