MCT mast cells |
MCT-ND2 |
CgA(124-143) |
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[mitocryptide-ND1] This peptide, Formyl-MPMANLLLLI, is a so-called mitocryptide (see also: cryptides). The peptide is derived from the N-terminus of the parent protein, which is MT-ND1 [mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1], known also as NADH dehydrogenase 1 or NADH-ubiquinone oxidoreductase chain 1, a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Unlike some other mitocryptides, the peptide does not cause cell activation of neutrophils, does not activate the neutrophil NADPH oxidase system, does not trigger superoxide release, and does not act as an agonist or antagonist for formyl peptide
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