MERS-CoV ORF4b |
MERS-CoV ORF8b |
nm23B |
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[Middle East respiratory syndrome coronavirus ORF5] this open reading frame in the genome of MERS-CoV [Middle East respiratory syndrome coronavirus], the causative agent of severe-to-fatal pneumonia, encodes one of several viral accessory proteins. MERS-CoV ORFb is a virulence factor that inhibits the induction of IFN-beta by inhibiting the function of the interferon regulatory factor IRF3 (Yang et al, 2013).
For other relevant entries see also the Pathogenicity/Virulence Factors Dictionary section of this encyclopedia.
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