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MES-13

A murine kidney mesangial cell line obtained from transgenic mice harbouring the early region of simian virus 40. The cells form colonies in soft agar in a colony formation assay and express the SV40 large T antigen (MacKay et al, 1988). The cells retain features characteristic of their normal counterparts despite their transformed phenotype and have been used extensively in the study of mesangial cell functions. The cells contract in response to angiotensin-2.

The conditioned medium of these cells contains large amounts of the murine chemokines MCP-1 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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