MMP-11 |
MMP-13 |
Hepatocyte growth factor activator inhibitor |
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[matrix metalloproteinase-12] Other designations for this protein are macrophage elastase, macrophage metalloelastase (EC3.4.24.65) (abbr. MME for mouse macrophage metalloelastase: HME for the human enzyme). The cDNA for HME has been cloned by Shapiro et al (1993) who demonstrated also that the protein (470 amino acids) is 64 % identical to the mouse protein.
MMP-12 is produced initially as in inactive proform that requires proteolytic activation. Raza et al (2000) have reported that plasmin and thrombin
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