MMP-7 |
MMP-9 |
q blast cells |
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[matrix metalloproteinase-8] This enzyme is a member of the family of matrix metalloproteinases. The human gene has been cloned by Hasty et al (1990) and Devarajan et al (1991). The murine gene has been cloned by Balbin et al (1998). Hu et al (1999) have identified non-secreted enzymatically active splice variant of human MMP-8. MMP-8, which is produced mainly by neutrophils and is called also neutrophil collagenase or PMNL collagenase [polymorphonuclear leukocyte collagenase]). It has been referred to as collagenase-2; abbr. CLG2 or CL-2 (Balbin et al, 2003).
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