NC cell growth factor |
NCCs |
GLFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC |
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[NC-specific cytotoxic factor] This biochemically uncharacterized factor of approximately 43 kDa is found in the conditioned medium of the murine IL3 dependent basophilic mast cell line, PT-18 (A17), and a rat basophilic leukemic cell line, RBL-2H3 (Okuno et al, 1986). The factor selectively lyses natural cytotoxic cell tumor targets, WEHI-164, but not natural killer cell sensitive targets or normal C3H/HeJ mouse embryonic fibroblasts.
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