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NRF

[neurite retraction factor] This biochemically uncharacterized factor of approximately 70 kDa is found in the conditioned medium of the human neuroblastoma/glioma hybrid cell line NG108-15. It reduces the retraction of neurites in morphologically differentiated cells grown in the presence of dibutyryl-cAMP in serum-free media. The factor differs from growth factors such as NGF, EGF, PDGF, FGF, NSILA, ECGF, and TGF (Ghahary et al, 1989).

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