neurospheres |
Neurotensin |
WFVGLKKNGSCKRG |
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abbr. NTT or NTN. This factor was found during a screen of a murine choroid plexus cDNA library. The murine and the human protein (395, and 397 amino acids, respectively, including a signal sequence of 22 amino acids) display 67 % identity. The protein shows features of a type 1 membrane protein (C-terminus inside). It does not contain the ELR sequence motif found in various chemokines. The human gene has been mapped to chromosome 16q. The factor is known also as SCYD1.
Neurotactin is a member of the family of chemotactic cytokines known as chemokines
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