PDGF-BB |
PDGF-CC |
Coronavirus ORF7a protein |
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[Platelet-derived growth factor-C] The protein is known also as SCDGF (Spinal cord-derived growth factor) or fallotein. It has a unique two-domain structure, containing an N-terminal region homologous to the extracellular CUB domain of neuropilin-1, and a C-terminal region consisting of a growth factor domain with homology to VEGF (25 %) and the PDGF A-chain (23 %) PDGF and VEGF domains.
PDGF-C is activated by cleavage of a site between the two domains, which then allows release of the growth factor domain from the
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