peroxisome proliferator-activated receptor-gamma-related protein |
pERp1 |
PENK(210-231) |
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(approved gene symbol) [p53 apoptosis effector related to PMP-22] The protein is known also as TP53 apoptosis effector. In databanks this protein is known also as KCP1 [keratinocyte-associated protein 1]. The protein has been described also as THW, a protein that acts as a tumor suppressor.
PERP has been identified by Attardi et al (2000) in a screen for genes that are targets of the tumor suppressor p53 and are involved in cell death by apoptosis. PERP is a tetraspan protein localizing to the plasma membrane and shows sequence similarity to the gas-3 protein (PMP22
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