ph91 antigen |
Phafin-1 |
SIS family of cytokines |
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[Phosphatase Actin Regulating Protein-1; phosphatase and actin regulator-1]. The cDNA has been identified independently as KIAA1733. In databanks the protein is being referred to also as RPEL1 [RPEL repeat containing 1] as the protein contains several RPEL motifs, which are known to be actin-binding sequence motifs.
PHACTR1 has been identified by Allen et al (2004). The protein is expressed predominantly in various regions of the brain, modulates the activity of PP1 [protein phosphatase 1] and binds to F-Actin.
Role in angiogenesis and cell death
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