PSG16 |
PSG18 |
BLECs |
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[pregnancy-specific glycoprotein 17] This murine glycoprotein, which is being referred to also as CEA2 [carcinoembryonic antigen 2] (Rudert et al, 1992), is a member of a larger family of pregnancy-specific glycoproteins secreted by the placenta (McLellan et al, 2005). Ha et al (2005) have reported that PSG17 induces the secretion of IL10, IL6, prostaglandin E(2), and TGF-beta-1 in macrophages. Waterhouse et al (2002) have reported that CD9 serves as a receptor for PSG17. Sulkowski et al (2011) have reported that PSG17 binds to CD9 and to cell surface proteoglycans.
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