PVNZ112.0-CBP |
PVNZ112.6-CBP |
Influenza virus CM2 protein |
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[Parapoxvirus of red deer in New Zealand chemokine binding protein ORF112.3; ORF112.3 chemokine binding protein] This virus-encoded chemokine binding protein has been identified by Sharif et al (2019) in Parapoxvirus of red deer in New Zealand (PVNZ), a species of the Parapoxvirus genus that causes pustular dermatitis.
The protein binds CXCL1, CXCL2, CXCL4, CXCL10, CCL5, CCL19, CCL21 and is thought to play a role in suppressing inflammation and the anti-viral immune response. Chemotaxis assays using neutrophils and monocytes shows that the chemokine binding protein
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