pro-PBP |
Properdin(143-161) |
GFR-alpha-3 |
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approved gene symbol: CFP [complement factor properdin [complement properdin P factor]. The protein is being referred to also as PFC [properdin factor complement] or simply as factor P. An older designation is complement factor P.
Properdin is a trimeric protein composed of identical 53 kDa subunits (Nolan et al, 1991) composed exclusively of seven type 1 thrombospondin repeats (Nolan et al, 1991; Sun et al, 2004; Tan et al, 2002). The protein can form form cyclic dimers, trimers, and tetramers (Smith et al, 1984). The human gene has been characterized by Nolan et al (1991). For a bioactive fragment of Properdin with activity in angiogenesis
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