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[PDGF- and VEGF-receptor related] also: DmVEGFR. This Drosophila melanogaster receptor is encoded by gene CG8222. Pvr is the sole member of the PDGF/VEGF family of receptors in Drosophila melanogaster. It has three ligands, Pvf1 [PDGF/VEGF factor-1], Pvf2 [PDGF/VEGF factor-2] (Harris et al, 2007), and Pvf3 [PDGF/VEGF factor-3] (Cho et al, 2002). Pvr is a receptor tyrosine kinase that has been implicated in a wide range of cellular functions.

Role in hematopoiesis

Munier et al (2003) have reported that Pvr and its ligand Pvf2 are required for ... ... ... ... ... Subscribe to continue reading! ... ...


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