Rig1 |
RIG-G |
FLS4.1 |
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[retinoic acid induced E] The expression of this protein is induced by the differentiation inducer all-trans-retinoic acid in a cell line derived from a patient with acute promyelocytic leukemia (Mao et al, 1996). RIG-E is a cell surface protein that shares some homology with CD59 and with a number of growth factor receptors. It shares high sequence homology with the murine Ly6 multigene family. Expression of RIG-E is not restricted to myeloid differentiation, because it is present also in thymocytes and in a number of other tissues at different levels.
Sequence comparisons show that the encoded protein is OIP-1 [osteoclast inhibitory peptide-1].
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