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RP38

[retinitis pigmentosa type 38] This term refers to a retinal dystrophy associated with defective phagocytosis of photoreceptor outer segments by the retinal pigment epithelium (RPE) and retinal degeneration. The underlying cause has been identified in the Royal College of Surgeons (RCS) rat as a mutation of a receptor tyrosine kinase gene. This receptor is mer (MERTK) (Gal et al, 2000).

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