SCC1
[susceptibility to colon cancer 1] This mouse gene has been cloned by Ruivenkamp et al (2002). The encoded protein is a receptor-type protein tyrosine phosphatase, protein tyrosine phosphatase-eta. In the nomenclature of CD antigens this protein has been given the designation CD148.
Ruivenkamp et al (2002) have found frequent deletions, loss of heterozygosity, and missense mutations in this gene in human cancers of colon, lung, and breast.
For additional information on CD antigens see also: CD antigens Dictionary.
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