STAMBP |
standard CD44 |
VASH |
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[Six-transmembrane protein of prostate 2] STAMP2 has been identified by Korkmaz et al (2005). STAMP2 displays a tissue-restricted expression with highest expression levels in placenta, lung, heart, and prostate and is predicted to code for a 459 amino acid six transmembrane protein. STAMP2 expression is androgen regulated in the androgen-sensitive, androgen receptor-positive prostate cancer cell line LNCaP, but not in androgen receptor-negative prostate cancer cell lines PC-3 and DU145. STAMP2 is overexpressed in prostate cancer cells compared with normal prostate epithelial cells. Ectopic expression of STAMP2 in prostate cancer cells significantly increases cell growth and colony growth in a colony formation assay
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