STK |
STK-1 ligand |
amyloid A4 |
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[stem cell tyrosine kinase-1] STK-1 was cloned from an enriched library of hematopoietic stem cells expressing the marker CD34 (Small et al, 1994). It is the human homolog of murine flk-2. It is identical with flt-3. In the nomenclature of CD antigens this protein has been given the designation CD135.
The cDNA encodes a protein of 993 amino acids with 85 % identity and 92 % similarity to the murine homolog. STK-1 is a member of the type 3 receptor tyrosine kinase family that includes kit, fms
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