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Scatter factor

abbr. SF (a term with multiple meanings). This factor is identical with HGF (hepatocyte growth factor) and is usually now referred to as HGF or HGF/SF (see: HGF for further information).

Scatter factor is produced by fibroblasts, smooth muscle cells, epithelial cells, keratinocytes and various other cell lines. It was isolated initially and characterized as a factor that influences the motility of cells at picomolar concentrations.

Scatter factor disrupts desmosomal junctions between epithelial cells and induces a motile fibroblast-like phenotype in individual cells ... ... ... ... ... Subscribe to continue reading! ... ...

 

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