SCRIB |
Scribble1 |
Agrin-11 |
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This is known also as SCRIB, Scribble1, murine circletail, and has been cloned independently as KIAA0147. A databank synonym is Vartul.
The gene was identified originally in Drosophila melanogaster (gene CG5462; scribbled; also being referred to as ird15 [Immune response deficient 15]), where mutations cause aberrant cell shapes and loss of the monolayer organization of embryonic epithelia (Bilder and Perrimon, 2000). Scribble is a cell junction-localized protein required for polarization
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