TDAG8 |
TDAPSFSDIPN |
oxidative stress response-associated microRNAs |
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[T-cell death-associated gene 51] This murine gene has been described by Park et al (1996). It is essential for expression of FAS antigen and concommitant susceptibility to activation-induced cell death by apoptosis in response to engagement of the T-cell receptor in T-cell hybridoma cells in vitro.
TDAG51 expression is induced by IGF-1 in NIH 3T3 cells. Toyoshima et al (2004) have shown that silencing of TDAG51 expression abolishes the ability of IGF-1 to rescue cells from serum starvation-induced cell death, suggesting that TDAG51 plays an important role in the
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