TIE2-expressing monocytes |
TIEG-1 |
GWKKWLRKGAKHLGQAAIKGLASamide |
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[TGF-beta-inducible early-response gene] This factor has been designated TIEG-1 [TGF-beta-inducible early-response gene-1], following the identification of a related factor, named TIEG-2 [TGF-beta-inducible early-response gene-2] (Cook et al, 1998). TIEG-3 [TGF-beta-inducible early-response gene-3] (Wang et al, 2004) is 96 % identical to TIEG-2 and 86 % to TIEG-1, respectively and differs from the other factors only in the lengths of their 3' UTRs. All three proteins are encoded by early response genes that are expressed in response to the antiproliferative growth factor TGF-beta
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