Tau-Interferon |
taurinergic neurons |
Ntra |
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[taurinergic neurons] These neurons use Taurine for neurotransmission and neuromodulation.
Taurine (2-amino-ethanesulfonic acid) is a sulfur-containing amino acid structurally similar to the neurotransmitters glycine and GABA [Gamma-aminobutyric acid]. It is synthesized from cysteine via oxidation of cysteine to cysteinesulfinate by cysteine dioxygenase (CDO), followed by the decarboxylation of cysteinesulfinate to hypotaurine, catalyzed by cysteine sulfuric acid decarboxylase (CSAD) (Jacobsen and Smith, 1968). Taurine is the second most abundant free amino acid in the central brain after glutamate, and the most abundant free amino acid in retina (Sturman, 1988).
In rat (Fletcher et al, 1996), goldfish (Omura and Inagaki, 2000; Nusetti et al, 2009) and Cynomologous monkey
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