Tenon's capsule fibroblasts |
TENP |
RG50862 |
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also: Tenon's capsule fibroblasts. These terms refer to a specialized type of fibroblasts is found in Tenon's capsule, a fibrous layer surrounding the globe of the eye from the ciliary margin of the cornea backwards to the entrance of the optic nerve. The cells play a key role in conjunctival repair and scarring (Khaw et al, 2001), become activated to promote wound healing such as cell proliferation and migration, the synthesis of extracellular matrix components (Ran et al, 2015), and autophagy (Zhang et al, 2014), and can proliferate and undergo phenotype transition from fibroblasts to myofibroblasts in the course of subconjunctival fibrosis upon stimulation by many fibrogenic factors, including
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