Thermotoga species ribosomal protein S23 |
Theromyzin |
NLRP7 |
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Theromacin is an antimicrobial peptide from the coelomic liquid of the leech Theromyzon tessulatum. Theromacin is a 75 amino acid cationic peptide containing 10 cysteine residues arranged in a disulfide array showing no similarities with other known antimicrobial peptides and belongs to the family of Macins. The peptide is active against Gram-positive bacteria. The gene is expressed in large fat cells in contact with coelomic cavities and the protein is immunodetected in large fat cells, in intestinal epithelia, and at the epidermis level. mRNA levels increase after blood meal ingestion and upon bacterial challenge, and a rapid release of the peptide
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