Arasin-like protein |
ARAYDFGLamide |
Caspase-6 |
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The cDNA encoding this antimicrobial peptide (65 amino acids) has been identified in hemocytes of the mud crab, Scylla paramamosain (Imjongjirak C et al, 2011). Its amino acid sequence has an overall sequence identity of 53% to arasin 2 from the spider crab, Hyas araneus. Expression in hemocytes is upregulated in response to change with Aerococcus viridans. A synthetic arasin-likeSp peptide has antimicrobial activity against both Gram-positive bacteria and Gram-negative bacteria including some crustacean pathogens (A. viridans, Vibrio harveyi and V. anguillarum).
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also:
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