atypical chemokine receptor 6 |
atypical ductal cells |
Cytochrome b5 reductase |
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[atypical chemokine receptor]
abbr. ACKRs. Individual receptors with this designation include ACKR1, ACKR2, ACKR3, ACKR4, ACKR5, ACKR6.
This collective term refers to a number of chemokine receptors that are considered atypical in the sense of being unable to elict signalling pathways upon ligand binding (for nomenclature see: Bacherlerie et al, 2014). These receptors are expressed mainly, but not exclusively, by cell types other than leukocytes, show promiscuous binding of inflammatory CC-Chemokines and CXC-Chemokines with high affinity, and sequester them, i.e., they act as
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