bursal peptide-8 |
bursal peptide I |
Shv |
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abbr. BP11. This peptide, DVAGKLPDNRT (Asp-Val-Ala-Gly-Lys-Leu-Pro-Asp-Asn-Arg-Thr) has been isolated by Liu et al (2011) from the chicken bursa of Fabricius, the central humoral immune organ unique to birds which plays important roles in B-lymphocyte differentiation. BP11, which is one of several other bursal peptides, promotes colony-forming units for pre-B-cells and regulates B-cell differentiation, including increase the percentage of immature and mature B-cells in bone marrow cells co-cultured with IL7. The peptide also shows an
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