Calcium-dependent guanylate cyclase activator protein |
calcium-mediated cell death |
NNKLCAKLGNGLKFNNGDICIKDSIN |
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[calcium ionophores]
Ionophores are compounds that increase the permeability of cellular membrane barriers to ions by functioning as mobile ion carriers or channel formers. They contain hydrophobic regions conferring lipid solubility and hydrophilic ion-binding regions that delocalise the charge of the ion to shield it from the hydrophobic regions of the membrane lipid bilayer.
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Calcium ionophore A23187 is an artificial mobile iron carrier that normally acts as an ion-exchange shuttle molecule transporting one divalent calcium ion into the cell in exchange of two H+. As intracellular calcium levels can be monitored by a variety of fluorescent probes use of
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