CoREST |
CORK1 |
ribosomal protein L11 |
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Corifollitropin alfa is a recombinant protein containing the alpha subunit of FSH [Follicle-stimulating hormone], which is shared with other glycoprotein hormones (see: glycoprotein hormones alpha peptide) and a recombinant hormone-specific beta subunit comprising the coding sequences of the beta subunit of FSH fused to the C-terminal peptide of the beta-subunit of hCG [human chorionic gonadotropin], which bears four O-linked oligosaccharide binding sites (Fares et al, 1992). Corifollitropin alfa interacts only with the FSH receptor and lacks luteinizing hormone activity (LaPolt et al, 1992). Corifollitropin alfa has a longer half life and an extended time-interval to peak serum
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